This March, 1916 cartoon deals with Mexico and United States borders. When Pancho Villa attacked Columbus, New Mexico on March 8-9, 1916, President Wilson retaliated with the punitive Mexican Expedition from March 14, 1916 to February 7, 1917 during the Mexican Revolution of 1910-1910. In this cartoon, Uncle Sam says "I've Had About Enough of This" as he jumps over the border fence with Mexico to chase after Pancho Villa.

Replica source: "Telegram from Secretary of State Robert Lansing to the American Embassy, London: Zimmermann Telegram as Received by the German Minister to Mexico," March 1, 1917, National Archives, Records of the Department of State, Record Group 59, National Archives Identifier 302025, Online Text. https://catalog.archives.gov/id/302025